Author(s): Manish Patel, Atul Sahu, Anish Chandy

Email(s): anishpharma@gmail.com

DOI: 10.52711/0975-4377.2026.00008   

Address: Manish Patel1, Atul Sahu1, Anish Chandy2*
1Students, Pharmaceutics Department, Chouksey School of Pharmacy, CEC, Bilaspur, CG.
2Associate Professor, Pharmaceutics Department, Chouksey School of Pharmacy, CEC, Bilaspur, CG.
*Corresponding Author

Published In:   Volume - 18,      Issue - 1,     Year - 2026


ABSTRACT:
A study was conducted on repaglinide, an antihyperglycemic agent, used in the management of non-insulin-dependent diabetes mellitus, to design and characterize bioadhesive buccal films to overcome hepatic first-pass metabolism. The films are prepared using various ratios of bioadhesive polymers like HPMC, chitosan, and carbopol. For elucidating the physicochemical compatibility between the drug and the used polymers, FT-IR spectroscopy was employed. The prepared films were evaluated for in vitro drug release, bioadhesion strength, swelling index, moisture absorption, and surface pH.


Cite this article:
Manish Patel, Atul Sahu, Anish Chandy. Fabrication and Characterization of Novel Repaglinide Incorporated Buccal Film for the Management of Type-2 Diabetes. Research Journal of Pharmaceutical Dosage Forms and Technology.2026; 18(1):47-1. doi: 10.52711/0975-4377.2026.00008

Cite(Electronic):
Manish Patel, Atul Sahu, Anish Chandy. Fabrication and Characterization of Novel Repaglinide Incorporated Buccal Film for the Management of Type-2 Diabetes. Research Journal of Pharmaceutical Dosage Forms and Technology.2026; 18(1):47-1. doi: 10.52711/0975-4377.2026.00008   Available on: https://www.rjpdft.com/AbstractView.aspx?PID=2026-18-1-8


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