Author(s):
Manish Patel, Atul Sahu, Anish Chandy
Email(s):
anishpharma@gmail.com
DOI:
10.52711/0975-4377.2026.00008
Address:
Manish Patel1, Atul Sahu1, Anish Chandy2*
1Students, Pharmaceutics Department, Chouksey School of Pharmacy, CEC, Bilaspur, CG.
2Associate Professor, Pharmaceutics Department, Chouksey School of Pharmacy, CEC, Bilaspur, CG.
*Corresponding Author
Published In:
Volume - 18,
Issue - 1,
Year - 2026
ABSTRACT:
A study was conducted on repaglinide, an antihyperglycemic agent, used in the management of non-insulin-dependent diabetes mellitus, to design and characterize bioadhesive buccal films to overcome hepatic first-pass metabolism. The films are prepared using various ratios of bioadhesive polymers like HPMC, chitosan, and carbopol. For elucidating the physicochemical compatibility between the drug and the used polymers, FT-IR spectroscopy was employed. The prepared films were evaluated for in vitro drug release, bioadhesion strength, swelling index, moisture absorption, and surface pH.
Cite this article:
Manish Patel, Atul Sahu, Anish Chandy. Fabrication and Characterization of Novel Repaglinide Incorporated Buccal Film for the Management of Type-2 Diabetes. Research Journal of Pharmaceutical Dosage Forms and Technology.2026; 18(1):47-1. doi: 10.52711/0975-4377.2026.00008
Cite(Electronic):
Manish Patel, Atul Sahu, Anish Chandy. Fabrication and Characterization of Novel Repaglinide Incorporated Buccal Film for the Management of Type-2 Diabetes. Research Journal of Pharmaceutical Dosage Forms and Technology.2026; 18(1):47-1. doi: 10.52711/0975-4377.2026.00008 Available on: https://www.rjpdft.com/AbstractView.aspx?PID=2026-18-1-8
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