Microspheres in Modern Pharmaceutics: A Comprehensive Review of Types, Techniques, and Advancements

Saransh Goyal; Sarika Gupta

doi:10.52711/0975-4377.2025.00028

Research Journal of Pharmaceutical Dosage Forms and Technology

ISSN

0975-4377 (Online)
0975-234X (Print)

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Microspheres in Modern Pharmaceutics: A Comprehensive Review of Types, Techniques, and Advancements

Author(s): Saransh Goyal, Sarika Gupta

Email(s): sarikagupta7017@gmail.com

DOI: 10.52711/0975-4377.2025.00028

Address: Saransh Goyal, Sarika Gupta*
Department of Pharmacy, Agra Public College of Higher Education and Research Centre, Agra-282007, India.
*Corresponding Author

Published In: Volume - 17, Issue - 3, Year - 2025

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ABSTRACT:
One of the innovative systems of delivering drugs, it provides a promising alternative to conventional and unit of fast-release preparation. Microspheres were generally characterized as a easily flowable powder, comprising synthetic polymer as well as proteins, these particles exhibit sizes between 1-1000µm. Microspheres exhibited a spherical morphology, thus their drug loading system exhibiting therapeutic effectiveness based on the properties which either alter materials, polymers, method or techniques applied. These were applied in the system of delivering drug which were formulated for acquiring sustained and rather than controlled-release formulation for better systemic availability and stability as well as act to a targeted site with predetermined rate. Microsphere encompass several types such as floating, bioadhesive, Magnetic, polymeric, radioactive microspheres which were developed with different techniques such as Solvent evaporation, Spray drying and spray congealing, Solvent extraction, Spray drying, Phase coacervation separation method, Single-phase emulsion method, Double--phase emulsion method, Quassisolvent emulsion evaporation-diffusion method. Thus, this review concludes that microsphere system of delivering drug offers a numerous advantages compared to conventional techniques, including controlled and sustained release. These systems also enable targeted drug delivery to various sites, such as ocular, intranasal, oral, and intravenous routes.

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Cite this article:
Saransh Goyal, Sarika Gupta. Microspheres in Modern Pharmaceutics: A Comprehensive Review of Types, Techniques, and Advancements. Research Journal of Pharmaceutical Dosage Forms and Technology.2025; 17(3):196-2. doi: 10.52711/0975-4377.2025.00028

Cite(Electronic):
Saransh Goyal, Sarika Gupta. Microspheres in Modern Pharmaceutics: A Comprehensive Review of Types, Techniques, and Advancements. Research Journal of Pharmaceutical Dosage Forms and Technology.2025; 17(3):196-2. doi: 10.52711/0975-4377.2025.00028 Available on: https://www.rjpdft.com/AbstractView.aspx?PID=2025-17-3-6

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