Mandesh Institude of Pharmaceutical Science and Reaserch Centre Mhaswad.
*Corresponding Author E-mail: amrutalokhande642@gmail.com
ABSTRACT:
Human personality is heavily influenced by hair, which is why we use so many cosmetic treatments to maintain it. Unlike synthetics, herbal formulations are always active and have either negligible or no side effects. The purpose of this study is to evaluate the value of polyherbal hair oil in treating common hair problems such dandruff and the most common forms of alopecia, balding, gray hair, dryness, and hair loss. Among the herbal ingredients in the mixture are Amla, almonds, garlic, mehendi powder, neem, castor oil, arendal oil, curry leaves, and coconut oil. All ingredients contain critical elements, including vitamins, antioxidants, protein, terpenoids, and several essential oils, necessary for the sebaceous glands to continue operating effectively. The organoleptic properties, acidity, saponification, and viscosity of the resulting oil and other characteristics were assessed.
KEYWORDS: Curry Leaves, Herbal, Pharmacological Activity, Murraya Koenigii.
INTRODUCTION:
Hair oils are mostly made of vegetable oil, to which small amounts of perfume are added. Castor, coconut, and sesame oils are some of the most commonly used vegetable fats. A hair oil unit is a project idea that appeals to potential entrepreneurs due to its broad usage and relatively easy processes. Ayurvedic hair oil is made from herbal extracts in hair oil bases like bringaraj, amla brahmi oil and other hair products are available. Most herbal hair oils are made primarily from vegetable oils and combined with a suitable perfume. Typical vegetable oils are castor, coconut, and oils that the taste of the sea.
Biological source: Dried leaves of Murraya koenigii Family: Rutaceae
Use: Prevents hair fall and premature greying of hair.
Curry leaves are a component of Murraya koenigii, a tiny, aromatic deciduous shrub of the Rutaceae family1. Human personalities are greatly influenced by their hair, which is also used to treat them with a variety of cosmetic products2. The study examined the effects of various concentrations of herbal oil on hair growth activity, refractive index, acid value, and saponification value3. In addition to sebaceous glands, sweat glands, and nails, hair is thought of as an integument's accessory structure and protective appendage. Hair is an essential part of the human body4. The three primary cyclic phases of hair growth are anagen, catagen, and telogen the main issues with hair include pigmentation issues, dandruff, and hair failure5. Curry leaves are utilized for their high protein content, their cleaning and softening properties, their promotion of scalp health, and their ability to stop hair loss6. Nonetheless, the use of emblica for any cause is only partially supported by clinical data7. The plant has tiny, trifoliate leaves with oval leaflets that range in green colour8. From seeds, two flavonoid glycosides, luteolin and quercetin, as well as steroidal saponins, have been isolated9. Curry leaf oil is also utilized in several herbal hair oils and hair tonics in European countries10. Ayurvedic and Siddha practitioners consider curry leaves
oil products to be sedative, antihelmentic, antidiabetic, antibacterial, antiviral, and contraceptive11.
Curry leaves dramatically lowered the levels of triglycerides (fat) and total cholesterol in an animal research by Xie et al. (2006). Curry leaves may have this hypolipidemic (lipid-lowering) effect due to their antioxidant content. It may have a possible effect in decreasing cholesterol and fat metabolism since it may help reduce cholesterol and low-density lipoprotein (bad cholesterol)12,13,14.
1. Accurately weigh all the dried and fresh herbs and leaves powder.
2. Mix coconut oil, arendal oil and castor oil uniformly.
3. After that mixing add almond oil, mehendi powder, Amla extract and keep aside for overnight.
4. Then add curry leaves, garlic, neem extract and boil until colour of curry leaves changes to dark brown colour.
5. After the colour change whole preparation was filtered through muslin cloth.
6. Finally small amount of color and flavoring agent was added to the oil.
7. It was placed in amber colored bottle.
8. Accurately weigh all the dried and fresh herbs and leaves powder.
9. Mix coconut oil, arendal oil and castor oil uniformly.
10. After that mixing add almond oil, mehendi powder, Amla extract and keep aside for overnight.
11. Then add curry leaves, garlic, neem extract and boil until colour of curry leaves changes to dark brown colour.
12. After the colour change whole preparation was filtered through muslin cloth.
13. Finally small amount of color and flavoring agent was added to the oil.
14. It was placed in amber colored bottle.
|
Sr. No. |
Ingredients |
Quantity (%) |
|
1 |
Amla |
6 |
|
2 |
Almond |
3 |
|
3 |
Garlic |
1 |
|
4 |
Mehendi powder |
3 |
|
5 |
Neem |
3.5 |
|
6 |
Curry leaves |
3.5 |
|
7 |
Arendal oil |
30 |
|
8 |
Castor oil |
30 |
|
9 |
Coconut oil |
20 |
Evaluation of Herbal Hair Oil:
A number of criteria, including pH, acid value, saponification value, refractive index, viscosity, and organoleptic parameters, were assessed for the prepared herbal oil 15,16.
1. Acid value:
10ml of oil was added with 25ml of ethanol and 25ml of ether. Phenolphthalein was added as indicator and titrated with 0.1M potassium hydroxide solution,
Acid value = 5.61n/w Where,
n= Number of ml of 0.1M KOH w= Weight of oil
2g of oil was accurately weighed and transferred into a 250ml of iodine flask. 25ml of 0.5 N alcoholic potassium hydroxide was added and boiled under reflux on a water bath for 30mins. Phenolphthalein was added as indicator and titrated against 0.5M HCl (‘a’ ml). Similarly blank was performed (‘b’ ml) without the sample.
Saponification Value: 28.05(b-a)/w Where, w= weight in grams of the solution.
pHof the herbal oil was detected using pH meter.
Viscosity was determined using Ostwald’s viscometer.
Specific gravity of the prepared oil was determined using pyknometer or specific gravity bottle.
It was determined using refractometer.
Colour, odour, skin irritation was determined manually. Oil was applied on hand and exposed to sunlight for 5mins to check for any irritation over skin.
Therapeutic Uses of curry Leaves:
The ability to fight microbes Using Murraya koenigii root extract in hexane, methanol, and chloroform, Bacillus subtilis, Staphylococcus aureus, Escherichia coli, Salmonella typhi, and fungal strains of Aspergillus niger, Candida albicans, and Trichophyton rubrum were assessed17
Murraya koenigii leaf extract in methanol and aqueous form was found to be effective against carrageenan-induced edoema in male albino rats at a concentration of 400 mg/kg, in contrast to petroleum ether and hexane extracts, which do not reduce inflammation.18.
The chemical component of M. koenigii, mahanimbine, was isolated from the petroleum ether extract of the dried plant using column chromatography. The anti-diabetic effect of the pure material was evaluated in Wistar rats given doses of 50 and 100 mg/kg of streptrozotocin.19
Isolated from the bark of Murraya koenigii, carbazole girinimbine substantially induces programmed cell death in HepG2 cells. The results of the study conducted in 2010 offered evidence for the involvement of mahanine in the arbitrated death receptor extrinsic route of apoptosis.20
Reactive oxygen species are often generated as metabolic byproducts of cell metabolism and external stimuli. ROS include the hydroxyl radical, singlet oxygen, These Reactive oxygen species disrupt homeostasis, which leads to oxidative stress and subsequent cell and tissue damage.21 Proteins, lipids, and nucleic acids are examples of biomolecules that can be harmed by high Reactive oxygen species levels.22 Age-dependent diseases like cancer, atherosclerosis, arthritis, and so forth are encouraged to start when unrestrained Reactive oxygen species accumulation occurs over the course of a person's lifetime.23 Plant-based natural antioxidants have been considered a potential therapy for the treatment and prevention of a number of diseases.24
The herbal ingredients were chosen for the formulation of hair oil. This research provides guideline on the use of herbal ingredients on the preparation of hair curry leaves hair oil having minimal or no side effects. The formulated hair oil is medicinally important in treatments of various other diseases. The formulation was proven to be safe for human use.
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12. from: https://www.ijppr.humanjournals.com/wp-content/uploads/2021/09/6.Dipak-Supe-Padmanabh- B.-Deshpande-Priyanka-Kandhare-Sandeep-Swami.pdf
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21. Dineshkumar B, Mitra A, Mahadevappa M. Antidiabetic and hypolipidemic effects of mahanimbine carbazole alkaloid from Murraya koenigii Rutaceae leaves. International Journal of Phytomedicine.
22. Samantaa SK, Kandimalla R, Gogoi BJ, Dutta KN, Choudhury P, De PK, Devi R, Pal BC, Talukdar NC, Phytochemical portfolio and anticancer activity of Murraya koenigii and its primary active component, mahanine, Pharmacological Research. 129; 2018: 227-236
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Received on 17.05.2024 Revised on 09.08.2024 Accepted on 08.10.2024 Published on 18.11.2024 Available online from December 19, 2024 Res. J. Pharma. Dosage Forms and Tech.2024; 16(4):350-352. DOI: 10.52711/0975-4377.2024.00054 ©AandV Publications All Right Reserved
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